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Atorvastatin calcium is an organic salt composed of calcium cations and Atorvastatin anions in a 1:2 ratio. Atorvastatin was first patented in 1986 and received FDA approval for medicinal use in 1996. It is listed as an essential medicine by the World Health Organization. It’s available as a brand-name drug called Lipitor but can also be purchased as a generic drug.
Atorvastatin acts by blocking HMG-CoA reductase, a liver enzyme involved in the production of cholesterol. It is a statin drug used to prevent cardiovascular disease and treat abnormal cholesterol levels in those who are at high risk. It is generally administered orally. The foetus may be harmed if used during pregnancy.
PRODUCT SPECIFICATIONS | |
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Name of Product | Atorvastatin Calcium |
IUPAC Name | calcium;(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate |
Synonyms | Lipitor; Sortis; Tahor; Atorvastatin Hemicalcium; Atorvastatin calcium salt |
CAS No | 134523-03-8 |
Molecular Formula | C66H68CaF2N4O10 |
Molecular Weight | 1155.3 g/mol |
Pubchem CID | 60822 |
Pubchem SID | 463960353 |
SR. No | Criteria | Limit/Specification |
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1 | Appearance (Color) | White to off-white |
2 | Appearance (Form) | Crystalline Powder |
3 | Solubility (in water) | Practically Insoluble |
4 | Melting Point | 198ºC |
5 | Solubility (in other solvents) | Soluble in Methanol |
6 | Long term Storage | 2-8ºC , dark |
The most prevalent adverse effects of Atorvastatin Calcium are:
Serious side effects include:
Q. Is Atorvastatin Calcium a blood thinner?
No, Atorvastatin isn’t a blood thinner. It’s a statin drug that works to help improve cholesterol problems and lower your risk for heart-related problems.
Q. What is Atorvastatin Calcium good for?
Atorvastatin, when combined with a healthy diet, can help lower “bad” cholesterol and fats (such as LDL and triglycerides) while increasing “good” cholesterol (HDL). It belongs to the “statin” class of medications. It works by lowering the amount of cholesterol the liver produces.
Q. What foods should be avoided when taking atorvastatin?
As part of your overall treatment with atorvastatin, avoid high-fat and high-cholesterol foods. Large amounts of grapefruit or grapefruit juice should be avoided because they can cause dangerous negative effects. Also, excessive alcohol consumption might lead to major liver disorders.