Cefuroxime is a 3-(carbamoyloxymethyl)cephalosporin compound. It is a semisynthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin with antibacterial activity. It was approved for medical use in 1977. It is included in the World Health Organization’s List of Essential Medicines. The common brand names under which Cefuroxime is sold in various countries are Zinacef, Axim, Rofurox, Kilbac, Xorimax, Ceftum, Supacef, Zamur, etc.
It is an antibiotic and kills bacteria by preventing them from building the necessary bacterial protective coating (cell wall). It is used to treat and prevent several bacterial infections including pneumonia, meningitis, otitis media, sepsis, urinary tract infections, etc. It is also used to prevent infections after surgery.
|Name of Product||Cefuroxime|
|IUPAC Name||(6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid|
|Synonyms||Cephuroxime; Cefuroxim; Cefuroximo; Cefuroxima; Cefuroximum; Zinacef; Sharox; cefurossima; Céfuroxime|
|Molecular Weight||424.4 g/mol|
|1||Appearance (Color)||White to Light Yellow to Light Beige|
|2||Appearance (Form)||Solid Powder or crystals|
|3||Solubility||Freely soluble as sodium salt (145 mg/L)|
|4||Melting Point||218-225 °C|
|5||PURITY (HPLC AREA %)||≥ 95.0 %||6||WATER||≤ 3.0 %||7||Proton NMR Spectrum||Conforms to Structure|
Cefuroxime is generally well tolerated, and its side effects are usually transient. The common side effects are as follows:
Serious side effects may include:
Q. What is Cefuroxime Axetil 500 mg used for?
Cefuroxime axetil is an acetoxyethyl ester prodrug of cefuroxime which is effective when taken by mouth. It is used to treat a wide variety of bacterial infections.
Q. How long does it take for Cefuroxime to work?
Cefuroxime is commonly prescribed for 5-10 days and should be taken every 12 hours, according to doctors. After taking the drug, it may take up to 48 hours for the symptoms to subside.
Q. Is Cefuroxime a penicillin?
Cefuroxime is a Cephalosporin antibiotic, chemically similar to Penicillin.
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