The hydrochloride salt derivative of fexofenadine, which has antihistaminic effect, is known as fexofenadine hydrochloride. It is a diarylmethane with long-lasting selective histamine H1 receptor antagonist. It is sold under the brand names like Allegra, Allegra-D, Mucinex Non-drowsy Allergy, Wal-fex, etc.
It was patented in 1979, but it wasn’t until 1996 that it was used in medical practice. It is included on the List of Essential Medicines published by the World Health Organization.
|Name of Product||Fexofenadine hydrochloride|
|IUPAC Name||2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid;hydrochloride|
|Synonyms||FEXOFENADINE HCL; Allegra; Telfast; Cloridrato de Fexofenadina; Fexofenadina cloridrato; Clorhidrato de fexofenadina; Chlorhydrate de fexofénadine|
|Molar Mass||538.1 g/mol|
|1||Appearance (Form)||Solid Powder|
|2||Appearance (Colour)||White to Beige|
|3||Solubility||DMSO: soluble ≥5 mg/mL|
The common side effects associated with the use of fexofenadine hydrochloride are as follows:
Side effects of fexofenadine that are serious but less prevalent include the following:
Q. Can dogs take fexofenadine hydrochloride?
Fexofenadine hydrochloride is a second-generation antihistamine that can be used to treat itching and other symptoms of allergic diseases in dogs and cats.
Q. What does fexofenadine hydrochloride do?
Q. Does fexofenadine hydrochloride make you sleepy?
It is less common for fexofenadine to cause drowsiness in contrast to other antihistamines since it does not quickly penetrate the blood–brain barrier.
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