Quetiapine Fumarate (111974-72-2)

Quetiapine Fumarate Chemical Structure

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What is Quetiapine Fumarate

Quetiapine Fumarate is a dibenzothiazepine. It’s a crystalline powder that’s white to off-white in colour and mildly soluble in water. It is a general prescription drug that shows antipsychotic activity and helps regulate mania (overexcitement) in bipolar patients and lowers schizophrenia symptoms including hallucinations and delusions.

Quetiapine was first discovered in 1985 and received US-FDA approval for medical usage in 1997. It is believed to work by blocking a number of receptors including serotonin and dopamine. It is sold under the brand name Seroquel. It is available as immediate-release and extended-release tablets.

Macsen Laboratories is the supplier of high-quality Quetiapine Fumarate.
Name of Product Quetiapine Fumarate
IUPAC Name 2-[2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethoxy]ethanol;but-2-enedioic acid
Synonyms Fumarato de Quetiapina; Fumarate de quétiapine; Quetiapina fumarato
CAS No 111974-72-2
Molecular Formula C29H33N3O10S
Molecular Weight C29H33N3O10S g/mol
Pubchem CID 73286

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Color) White to off-white
2 Appearance (Form) Solid Powder
3 Melting Point 174ºC
4 Long term Storage 2-8ºC , dark


  • This medicine is used to treat schizophrenia and other mental/mood disorders (a mental illness that causes disturbed or unusual thinking, depression, and strong or inappropriate emotions).
  • Adults and children over the age of ten are prescribed quetiapine to treat bipolar disorder (manic depression).
  • It is useful in the treatment of major depressive disorder either taken alone or in combination with other drugs (MDD).
  • It is a medication that is widely used for the treatment of Parkinson’s disease.

Side effects

The common side effects associated with the use of Quetiapine Fumarate are as follows:

  • Fever, Dry mouth, dizziness, cough and body aches.
  • Vomiting, Abdominal pain, Dyspepsia, Hypertension, High blood cholesterol, Pharyngitis, and Dysphagia

The rare side effects associated with the use of Quetiapine Fumarate are as follows:


Q. Is Quetiapine fumarate a sleeping pill?

The Food and Drug Administration (FDA) has not approved quetiapine for insomnia treatment. It is, however, occasionally prescribed off-label as a short-term sleep aid due to its sedative properties.

Q. Is Quetiapine the same as Xanax?

Psychiatric illnesses are treated with Seroquel (quetiapine) and Xanax (alprazolam). Seroquel is a medication that is used to treat schizophrenia, bipolar disorder, and significant depression whereas Xanax is used in the treatment of anxiety disorders and panic attacks.

Q. How long before bed should I take quetiapine?

The dose should be taken 3-4 hours before bedtime, once a day. It is critical that you follow your health care provider’s instructions.

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