Clopidogrel Bisulfate (120202-66-6)

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What is Clopidogrel Bisulfate

Clopidogrel bisulfate belongs to the thienopyridine class of drugs. It was patented in 1982 and approved for medical use in 1997. It is on the World Health Organization’s List of Essential Medicines. It is an antiplatelet- drug and works by irreversibly inhibiting a receptor called P2Y₁₂ on platelets.

Plavix is one of the many brand names for it. After a heart attack, severe chest pain (angina), or circulation difficulties, clopidogrel is used to reduce your risk of having a stroke, blood clot, or major heart disease. Platelet inhibition can be seen two hours after taking a single dose of oral clopidogrel, but because the beginning of action is slow, a loading dose of 600 or 300 mg is used when a quick effect is required.

Uses

• Clopidogrel is used to prevent heart attack and stroke in people who are at high risk of these events, including those with a history of myocardial infarction and other forms of acute coronary syndrome.
• In those with peripheral artery disease, Clopidogrel is used to avoid significant or life-threatening problems with the heart and blood arteries.
• It’s also used in conjunction with acetylsalicylic acid (ASA, aspirin) to prevent thrombosis after placement of a coronary stent or as an antiplatelet medication for patients who can’t take aspirin.
• In persons with a history of stomach ulceration, consensus-based treatment guidelines advise using clopidogrel instead of aspirin (ASA) for antiplatelet therapy.

Side effects

Common side effects associated with Clopidogrel bisulfate include:

• Excessive tiredness
• Headache
• Dizziness
• Nausea and vomiting
• Stomach pain
• Diarrhoea

Some of the negative effects are potentially dangerous. Call your doctor right away if you see any of the following symptoms:

• Rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, and trouble breathing
•  Thrombotic thrombocytopenic purpura -Nosebleeds, pale skin, easy bruising, purple spots under your skin or in your mouth
• Low blood sugar–headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky
• Signs of a blood clot–sudden numbness or weakness, confusion, problems with vision or speech
• Bloody/red/pink/dark urine

FAQs

Q. Is clopidogrel bisulfate a blood thinner?

Clopidogrel is an antiplatelet blood-thinning medicine that inhibits platelet aggregation and thus inhibits aspects of blood clotting.

Q. What is the difference between Aspirin and Clopidogrel?

Clopidogrel is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID).

Q. Is clopidogrel bisulfate an anticoagulant?

Clopidogrel is an anticoagulant used to treat patients with acute coronary syndrome, heart attack (myocardial infarction), peripheral vascular disease, and ischemic strokes.