Duloxetine Hydrochloride (136434-34-9)

Duloxetine hydrochloride Chemical Structure

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What is Duloxetine hydrochloride

Duloxetine hydrochloride is a fluoxetine derivative that belongs to the class of selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) and has antidepressant properties. It was approved for medical use in the United States and in the European Union in 2004. It is available as a generic medication.

Depression and anxiety are treated with duloxetine. It is also used to treat nerve pain (peripheral neuropathy) in patients who have diabetes or who have ongoing pain from medical illnesses such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).

Macsen Laboratories is the supplier of high-quality Duloxetine hydrochloride.
Name of Product Duloxetine hydrochloride
IUPAC Name (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;hydrochloride
Synonyms DULOXETINE HYDROCHLORIDE; Duloxetine HCl; Cymbalta; Ariclaim; Xeristar; Cloridrato de Duloxetina; Duloxetina cloridrato; Clorhidrato de duloxetina; Chlorhydrate de duloxétine
CAS No 136434-34-9
Molecular Formula C18H20ClNOS
Molecular Weight 333.9 g/mol
Pubchem CID 60834

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Color) White to off-white
2 Appearance (Form) Solid Powder
3 Melting Point 161ºC
4 Long term Storage 2-8ºC , dark


Duloxetine Hydrochloride is used in the management of the following disorders:

Side effects

Common side effects associated with Duloxetine hydrochloride are:

  • Nausea
  • Dry mouth
  • Constipation
  • Loss of appetite
  • Tiredness and drowsiness
  • Increased sweating
  • Increased blood pressure

Sexual dysfunction, withdrawal syndrome resembling SSRI discontinuation syndrome and increased suicidal tendency in persons younger than 25 are also reported with Dulotexine hydrochloride.


Q. Is Duloxetine Hydrochloride a narcotic?

Duloxetine belongs to a group of drugs called selective norepinephrine reuptake inhibitors (SNRIs). It is not a narcotic.

Q. Is Duloxetine a sleeping pill?

Duloxetine has been shown to increase mood, sleep, appetite, and vitality while also reducing anxiousness. It can also help with pain from medical disorders.

Q. Can Duloxetine cause liver damage?

Duloxetine is generally well tolerated, however, it might cause liver enzyme elevations and, in rare circumstances, liver damage.

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