Gemifloxacin Mesylate (210353-53-0)

Gemifloxacin Mesylate Chemical Structure

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What is Gemifloxacin Mesylate

Gemifloxacin mesylate is the mesylate salt of gemifloxacin, which is a naphthyridine and fluoroquinolone derivative, antibacterial agent. It is a quinolone with a broad-spectrum activity used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations, commonly sold under the trade name Factive.

Macsen Laboratories is the supplier of high-quality Gemifloxacin Mesylate with ISO certification.
PRODUCT SPECIFICATIONS
Name of Product Gemifloxacin mesylate
IUPAC Name 7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid
Synonyms Factive; Gemifloxacin mesilate; Gemifloxacin methanesulfonate; mesilato de gemifloxacina; Gemifloxacina mesilato; Mésylate de gémifloxacine
CAS No 210353-53-0
Molecular Formula C19H24FN5O7S
Molar Mass 485.5 g/mol
Pubchem CID 9588170

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Form) Powder
2 Appearance (Colour) White to light brown
3 Solubility (in water) 10 mg/mL, clear
4 Storage temp. Room temperature
5 Assay ≥98% (HPLC)

Uses

  • Acute bacterial exacerbation of chronic bronchitis (ABECB) caused by Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, or Moraxella catarrhalis.
  • Community-acquired pneumonia (of mild to moderate severity) caused by Streptococcus pneumoniae (including multi-drug resistant strains [MDRSP]), Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Chlamydia pneumoniae, or Klebsiella pneumoniae.

Side effects

The most common side effects include:

  • Nausea and vomiting
  • Stomach pain
  • Diarrhoea,
  • Dizziness and headache
  • Rash

The major serious side effects include:

FAQs

Q. Is gemifloxacin available in the US?

Due to manufacturing and regulatory concerns, Factive (gemifloxacin) has not been available in the United States in recent years.

Q. Is gemifloxacin a penicillin?

Gemifloxacin belongs to the class of fluoroquinolone antibiotics. It works by eliminating pathogenic microorganisms.

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