Pregabalin is a 3-isobutyl derivative of gamma-aminobutyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities. It was approved for medical use in the United States in 2004 and was developed as a successor to gabapentin. Pregabalin is classified as a Schedule V controlled substance in the United States under the Controlled Substances Act of 1970. In the United Kingdom, it is classified as a Class C controlled substance.
It is a gabapentinoid and acts by inhibiting certain calcium channels. Pregabalin comes as a capsule, a solution, and an extended-release tablet. All forms are taken by mouth. It is generally used to treat epilepsy, neuropathic pain, fibromyalgia, restless leg syndrome, opioid withdrawal and generalized anxiety disorder.
|Name of Product||Pregabalin|
|IUPAC Name||(3S)-3-(aminomethyl)-5-methylhexanoic acid|
|Synonyms||Pregabalin, Lyrica, 3-isobutyl GABA, (S)-3-(Aminomethyl)-5-methylhexanoic acid|
|Molecular Weight||159.23 g/mol|
|1||Appearance (Color)||White to off-white|
|2||Appearance (Form)||Crystalline Solid|
|3||Solubility||Freely soluble in water|
|4||Melting Point||176 - 178ºC|
|5||Boiling Point||144 - 147 ºC||6||Uses||Seizures, Neuropathic Pain, Anxiety disorders|
The more common side effects of pregabalin include:
Serious side effects include:
Addiction may happen when pregabalin is taken in high dosages over a long period of time, but the risk is low when taken in normal amounts. The safety of using it during pregnancy or breastfeeding is unknown.
Q. Is Pregabalin a controlled substance?
Pregabalin is, indeed, a regulated substance. It is a prescription medicine classed under schedule V. Schedule V medicines have established medical usefulness, but they can also develop psychological or physical dependence. This suggests that the substance could be abused.
Q. Is Pregabalin the same as Lyrica?
Lyrica is a brand name prescription medication containing Pregabalin as the active pharmaceutical ingredient.
Q. How Pregabalin differs from Gabapentin?