Raloxifene hydrochloride (82640-04-8)

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What is Raloxifene hydrochloride

Raloxifene Hydrochloride is the hydrochloride salt form of raloxifene, a second-generation selective estrogen receptor modulator (SERM). It is used to help prevent and treat thinning of the bones (osteoporosis) only in postmenopausal women. Raloxifene was approved for medical use in the United States in 1997. It is available as a generic medication.

Uses

• It is used to treat and prevent osteoporosis in postmenopausal women, in conjunction with calcium and vitamin D supplements, at a dosage of 60 mg per day.
• It is also used to reduce the chance of developing invasive breast cancer (breast cancer that has progressed beyond the milk ducts or lobules into the surrounding breast tissue) in postmenopausal women at high risk of developing this type of cancer or with osteoporosis.

Side effects

Common side effects associated with the use of Raloxifene hydrochloride are:

• Hot flashes (more common in the first 6 months of raloxifene therapy)
• Leg cramps
• Vaginal dryness
• Swelling of the hands, feet, ankles, or lower legs
• Difficulty falling asleep or staying asleep

Raloxifene may cause severe blood clots to form in the legs, lungs, or eyes. It may also increase the risk of deep vein thrombosis and pulmonary embolism in postmenopausal women. Raloxifene also possesses teratogenic properties.

FAQs

Q. Is raloxifene the same as raloxifene hydrochloride?

Raloxifene Hydrochloride is the hydrochloride salt form of raloxifene.

Q. Is raloxifene an estrogen?

Raloxifene is a selective estrogen receptor modulator that affects the uterine endometrium, breast tissue, and lipid metabolism in estrogen-agonistic and estrogen-antagonistic ways, respectively.

Q. What time of day should you take raloxifene?

Raloxifene can be taken whenever you find it easiest to remember, but try to take your dosages every day at the same time.

Q. Does raloxifene make you gain weight?

It’s possible that using this medication will make you gain some weight, however, the chances are less.

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