Tenofovir Disoproxil Fumarate is an adenine analogue. It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA). It is sold under the trade name Videar among others and is generally used with other antiretrovirals to treat chronic hepatitis B and to prevent and treat HIV/AIDS. It is available in combinations such as emtricitabine/tenofovir, efavirenz/emtricitabine/tenofovir, and elvitegravir/cobicistat/emtricitabine/tenofovir.
Tenofovir was licensed for use in the United States in 2001 after being patented in 1996. It is listed as an essential medicine by the World Health Organization. As of 2017, it is available as a generic drug in the United States.
|Name of Product||Tenofovir Disoproxil Fumarate|
|IUPAC Name||[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate;but-2-enedioic acid|
|Synonyms||Fumarato de Tenofovir Desoproxila; Tenofovir disoproxil fumarato; Fumarato de disoproxilo de tenofovir; Fumarate de ténofovir disoproxil|
|Molecular Weight||635.5 g/mol|
|2||Appearance (Form)||Fine, powder-like crystals|
|3||Solubility (in water)||13.4 mg/mL at 25 °C|
|5||Long term Storage||2-8ºC , dark|
The most common side effects associated with the usage of tenofovir disoproxil are:
Long term usage side effects include:
Q. When is the best time to take tenofovir disoproxil fumarate?
Tenofovir pills should be taken with a meal or snack.
Q. Does tenofovir cause liver damage?
Tenofovir does not appear to be a substantial contributor to liver harm caused by drugs.
Q. How long does it take for tenofovir to work?
When administered in combination with other antiretrovirals, tenofovir usually begins to function within the first four weeks, resulting in a substantial reduction in HIV viral load (amount of HIV virus in your blood). The viral load in a vast proportion of patients reduces to undetectable levels within three to six months.