Valsartan is a nonpeptide triazole-derived antagonist of angiotensin (AT) II receptor with antihypertensive properties. It was patented in 1990 and came into medical use in 1996. It is available as a generic medication. It works by relaxing blood vessels so that blood can flow more easily. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
Valsartan is active orally and is taken by mouth. Valsartan/hydrochlorothiazide, valsartan/amlodipine, valsartan/amlodipine/hydrochlorothiazide, and valsartan/sacubitril are some of the available combinations for medical use.
|Name of Product||Valsartan|
|IUPAC Name||(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid|
|Synonyms||Diovan; Tareg; Provas; Exforge; Valsartana; valsartán|
|Molecular Weight||435.5 g/mol|
|2||Appearance (Form)||Solid Powder|
|3||Melting Point||116-117 °C|
|4||Solubility||Soluble in ethanol, DMSO, and dimethyl formamide|
|5||Stability/Shelf Life||Stable under recommended storage conditions|
Common side effects include:
Other potentially harmful side effects include:
Use during pregnancy can be harmful to the infant. Also, Valsartan is not recommended for breastfeeding mothers.
Q. Is Valsartan a beta-blocker?
Valsartan is an Angiotensin II receptor blocker (ARBs) used to treat hypertension, heart failure, and heart attack recovery.
Q. Does Valsartan cause weight gain?
Valsartan’s most common adverse effects are minor and short-lived. However, people who used the medicine also suffered weight gain and hair loss.
Q. Why was Valsartan taken off the market?
In July 2018, the FDA announced a voluntary recall of several drugs containing valsartan (Amlodipine/Valsartan Tablets USP, Valsartan HCTZ Tablets, and Valsartan Tablets USP) due to the detection of trace amounts of cancer-causing chemical N-nitrosodiethylamine (NDEA).
The valsartan-containing medications Diovan, Entresto, Exforge, and Exforge HCT are not currently included in the recall.
Q. Is Valsartan safe to take in 2022?
Valsartan is generally considered safe and non-toxic, but the drug should always be taken as per the directions by your physician.
Q. Is Valsartan an ACE inhibitor?
Valsartan is in a class of medications called angiotensin II receptor antagonists. It is not an angiotensin-converting enzyme (ACE) inhibitor.