Ferrous Fumarate Chemical Structure

What is Ferrous Fumarate?

The fumarate (dicarboxylic acid) salt of the mineral iron is Ferrous Fumarate or Iron(II) fumarate. It is a type of dietary iron supplement that is mostly used to treat or prevent iron deficiency anemia, a condition characterized by low levels of red blood cells due to insufficient iron in the body.

Macsen Laboratories is the supplier of high-quality Ferrous Fumarate.
Name of Product Ferrous Fumarate
IUPAC Name (E)-but-2-enedioate;iron(2+)
Synonyms Iron(II) fumarate; Feostat; Ferreus Fumarate; Fumarate ferreux; Fumarato ferroso
CAS No 141-01-5
Molecular Formula C4H2FeO4
Molar Mass 169.90 g/mol
Pubchem CID 6433164

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Form) Solid Powder
2 Appearance (Color) Reddish-orange to Reddish-brown
3 Odor Odorless
4 Density 2.435 g/cm3 (20 °C)
5 Melting point 280 °C (536 °F; 553 K)
6 Solubility Very soluble in alcohol
Slightly soluble in water
7 Loss on Drying (at 105°C ) NMT 1.0% w/w


Ferrous fumarate is a type of iron supplement, having the following primary uses-

  • Iron Deficiency Anemia Treatment: Ferrous fumarate is often prescribed to individuals with iron deficiency anemia to replenish their iron stores and increase the production of healthy red blood cells. It helps improve symptoms such as fatigue, weakness, pale skin, and shortness of breath.
  • Treatment of Iron Deficiency in Chronic Conditions: Certain chronic diseases or conditions, such as chronic kidney disease, inflammatory bowel disease, and gastrointestinal disorders, can lead to iron deficiency. Ferrous fumarate may be prescribed as part of the treatment plan to address the underlying iron deficiency.
  • Iron Supplementation: Ferrous Fumarate is used as a dietary supplement and is prescribed to pregnant women who are at risk of iron deficiency or anemia. It can also be used to meet the iron needs of individuals following a vegetarian or vegan diet, who have an increased risk of iron deficiency due to limited intake of dietary iron.

Side effects

Side effects associated with the use of Ferrous Fumarate are as follows –

  • Nausea & Vomiting
  • Constipation
  • Stomach Cramps
  • Diarrhea
  • Darkening of stools
  • Allergic reactions (in rare cases)


Q. What is the difference between Ferrous Fumarate and Ferrous Sulfate?

Both Ferrous Fumarate and Ferrous Sulfate are used as iron supplements. The major difference between the two is that, in ferrous fumarate, ferrous ion is coupled with an organic anion whereas the anion in ferrous sulfate is inorganic. Also, ferrous fumarate is reddish-brown in color and ferrous sulfate exists in different colors, the most common heptahydrate form being blue-green in color.

Q. Can Ferrous Fumarate be taken with Omeprazole?

Individuals who are iron-deficient or are suffering from anemia, should consult their physician before taking ferrous fumarate with Omeprazole. This is because omeprazole may impair iron absorption by lowering stomach acid, making ferrous fumarate less effective in treating the disease.

Q. Can Ferrous Fumarate cause high blood pressure?

There are no evidences suggesting that ferrous fumarate can directly cause hypertension.

Q. Can I take ibuprofen with ferrous fumarate?

There are no reported interactions between ibuprofen and ferrous fumarate. However, one should take advice from a registered medical practitioner for a personalized suggestion based on their specific situation.

Q. Is Ferrous Fumarate available over the counter?

Ferrous Fumarate is available both over the counter (OTC) and as a prescription medication, depending on the country and specific regulations in place.

Q. Does Ferrous Fumarate cause weight gain?

Ferrous fumarate does not directly contribute to weight gain. However, some individuals may experience changes in appetite or digestive discomfort when taking iron supplements, which could indirectly affect eating habits and weight.

Q. How long does Ferrous Fumarate take to work?

The majority of people begin to feel better within a week, but it may take up to four weeks for the medication to exert its maximum effect.

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