Acid Red 94 or Rose Bengal is an organic compound and belongs to the class of xanthenes. In 1882, Swiss chemist Robert Ghnem synthesized rose bengal as a 4,5,6,7-tetrachloro 2′,4′,5′,7′-tetraiodofluorescein analogue. It is a commonly used dye for detecting damage to the ocular surface epithelium in ocular surface diseases like dry eye and herpetic keratitis.
|Name of Product||Rose bengal disodium salt|
|Synonyms||Rose Bengal sodium salt; Xantryl; Food Red No. 105, sodium salt; PV 10; C.I. Acid Red 94; Rosa Bengala; Rosa del Bengala; Rose Bengale|
|Molecular Weight||1017.6 g/mol|
|Other available variants|| Rose Bengal Sodium (11121-48-5)
Rose Bengal Lactone (4159-77-7)
|1||Appearance (Form)||Solid powder|
|2||Appearance (Color)||Dark Violet|
|4||Storage temp.||Room temp.|
Q. What is Rose Bengal test?
The Rose Bengal test (RBT) is a rapid slide-type agglutination assay performed with a stained B. abortus suspension at pH 3.6–3.7 for the serological diagnosis of brucellosis.
Q. What is the difference between Rose Bengal stain and fluorescein?
Rose Bengal is actually a derivative of fluorescein, however, unlike fluorescein it is not a vital dye. Fluorescein staining manifests whenever there is disruption of cell-cell junctions whereas rose bengal staining ensues whenever there is deficiency of preocular tear film protection. Fluorescein is distinguishable from rose bengal by its absence of inherent toxicity and photodynamic activity.