Climbazole (38083-17-9)

Climbazole Chemical Structure

What is Climbazole?

Climbazole is a member of monochlorobenzenes, a member of imidazoles, an aromatic ether, a ketone and a hemiaminal ether. It is used in various personal care products and topical medications used for the treatment and prevention of fungal infections, particularly those affecting the skin and scalp.

It is commonly found in anti-dandruff shampoos, scalp treatment and hair care products, and topical antifungal creams.

Macsen Laboratories is the leading supplier of Climbazole with ISO certification.
Name of Product Climbazole
IUPAC Name 1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one
Synonyms Climbazole; Baypival; Climbazol; Crinipan AD; Climbazolum
CAS No 38083-17-9
Molecular Formula C15H17ClN2O2
Molecular Weight 292.76 g/mol
Pubchem CID 37907

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Form) Solid Powder
2 Appearance (Color) White to Off-white
3 Solubility Soluble in DMSO & Ethanol
Insoluble in Water
4 Melting Point Between 94.0 to 98.0 °C
5 Loss on Drying (50°C, under vacuum) NMT 0.5 %
6 Sulfated Ash NMT 0.20 %


  • Climbazole is a common active constituent found in anti-dandruff shampoos. It controls and reduces dandruff by inhibiting the growth of Malassezia spp. fungi, which are known to contribute to the formation of dandruff.
  • It can be found in lotions, creams, and serums designed to treat scalp conditions such as seborrheic dermatitis, scalp psoriasis, and fungal infections.
  • It can also be used as an active ingredient in topical creams or ointments for the treatment of various fungal infections of the skin, such as athlete’s foot, jock itch, and ringworm.

Side effects

The side effects which may be caused due to the use of Climbazole are as follows-

  • Skin irritation, including redness, itching, or a burning sensation at the application site.
  • Increased sensitivity to sunlight (photosensitivity) in some individuals.
  • May cause temporary dryness or changes in the texture of the hair.


Q. Is Ketoconazole and Climbazole same?

Ketoconazole and Climbazole are both broad-spectrum antifungal agents used in topical products like shampoos and conditioners for the management of dandruff, seborrheic dermatitis, and scalp fungal infections. However, they both have different chemical structures and properties. Also, ketoconazole is only available as a prescription medication whereas Climbazole  is often found in over-the-counter personal care products.

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