4-Butylresorcinol (18979-61-8)

4-Butylresorcinol Chemical Structure

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What is 4-Butylresorcinol ?

4-Butylresorcinol also referred to as 4-n-butylresorcinol, belongs to the resorcinol’s family. It has the ability to lighten and brighten the skin by inhibiting the activity of tyrosinase, the rate-limiting melanogenic enzyme.

Macsen Laboratories is the leading manufacturer and supplier of 4-Butylresorcinol with ISO certification.
PRODUCT SPECIFICATIONS
Name of Product 4-Butylresorcinol
IUPAC Name 4-butylbenzene-1,3-diol
Synonyms Butylresorcinol; Rucinol; Resorcinol, 4-butyl-; 4-n-Butylresorcinol; Kopcinol
CAS No 18979-61-8
Molecular Formula C10H14O2
Molecular weight 166.22 gm/mol
Pubchem CID 205912

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Form) Solid Powder or Crystals
2 Appearance (Color) White to Beige or Pink
3 Solubility Soluble in organic solvents
Poorly soluble in water
4 Melting Point 53°C
5 Flash Point 145°C

Mechanism of Action

Hyperpigmentation is a common condition that affects the skin. It is caused by the buildup of melanin in particular areas or patches of the skin, which causes those areas to look darker than the surrounding area of skin. It can occur because of aging or disorders like melasma. Enzyme tyrosinase is the most important regulator of melanin synthesis.

4-n-Butylresorcinol inhibits directly the activities of tyrosinase and tyrosinase-related protein-1 (TRP-1), which are enzymes necessary for the production of melanin pigment and thus inhibits melanin production.

Uses

  • It is frequently found in cosmetics used for hyperpigmentation, where it serves the purpose of a depigmenting agent.
  • In addition to this, it is an extremely efficient skin-whitening agent that can help reduce the appearance of age spots.

FAQs

Q. Is 4-butylresorcinol safe?

It is found that in addition to being  highly effective as a depigmenting agent, it is very well tolerated with extremely rare cases of skin sensitivity. Further, it can also be used during pregnancy.

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