Acetamide Chemical Structure

What is Acetamide?

Acetamide, also referred to as Ethanamide, is an organic compound with the chemical formula CH3CONH2. It is a simple amide derived from acetic acid. Chemically, the molecule consists of an acetate group (CH3CO) linked to an amino group (NH2). It occurs as colorless to gray solid and is hygroscopic in nature.

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Name of Product Acetamide
IUPAC Name acetamide
Synonyms Ethanamide; Acetic acid amide; Acetylamine
CAS No 60-35-5
Molecular Formula CH3CONH2
Molecular Weight 59.07 g/mol
Pubchem CID 178


SR. No Criteria Limit/Specification
1 Appearance (form) Solid Crystals
2 Appearance (color) Colorless
3 Odor Odorless when pure, but frequently has a mousy odor
4 Solubility Very soluble in water
Soluble in chloroform, glycerol, hot benzene
Slightly soluble in ether
5 Melting point 79 to 81 °C
6 Density 1.159 g/cm3
7 Acidity (pKa) 15.1 (25 °C, H2O)


  • Acetamide is used as a solvent for various organic and inorganic substances.
  • It serves as an precursor or intermediate in the synthesis of various chemicals, e.g. thioacetamide.
  • It is used as a plasticizer, a substance added to polymers to improve their flexibility, durability, and processability.
  • Further applications of acetamide include electrochemistry and as a reagent in organic synthesis of pharmaceuticals, insecticides, and plastic antioxidants.
  • In laboratory settings, acetamide can be used as a reagent for certain experiments and reactions.


Q. Is acetamide an amine or amide?

Acetamide has amide functional group.

Q. Is acetamide acid or base?

When acetamide dissolves in water, hydroxyl (OH-) ions are produced. So, it acts as a weak base in an aqueous solution. In liquid NH3, acetamide dissolves to produce ammonium (NH4+) ions. Thus, in liquid ammonia, it functions as a mild acid.

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