Avobenzone Chemical Structure

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What is Avobenzone?

Avobenzone is a dibenzoyl methane derivative. It is an oil-soluble ingredient used in sunscreen products. However, it is susceptible to photodegradation, and therefore it is important that avobenzone be combined with photostabilizers in the final sunscreen product. It has an absorption maximum of 357 nm. It was granted a patent in 1973 and received EU approval in 1978. The FDA gave its approval in 1988.

Macsen Laboratories is the leading supplier of Avobenzone with ISO certification.
Name of Product Avobenzone
IUPAC Name 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione
Synonyms Parsol 1789; Butyl methoxydibenzoylmethane; Escalol 517; Eusolex 9020; NeoHeliopan 357; 4-tert-butyl-4'-methoxydibenzoylmethane; Avobenzona
CAS No 70356-09-1
Molecular Formula C20H22O3
Molecular Weight 310.4 g/mol
Pubchem CID 51040
Pubchem SID 475775548


SR. No Criteria Limit/Specification
1 Appearance (Form) Solid Powder or Crystals
2 Appearance (Color) White or Slightly Yellow
3 Odor Slightly aromatic
4 Solubility Soluble in isopropanol, decyl oleate, capric/caprylic triglyceride, castor oil
Insoluble in water
5 Melting point 81-84 °C
6 Log P log Kow = 4.51 (estimated)

Mechanism of action

Avobenzone is a UV rays blocker used in sunscreen. Avobenzone is a topical UV protector with a broad spectrum of protection against UV radiation. It inhibits UVA I, UVA II, and UVB wavelengths, which reduces the damaging effects of UV rays on skin.


Avobenzone is a UVA solar filter and is used in sunscreen lotions and cosmetic formulations. It protects the skin from sunburn-causing UV rays. Using sunscreen products containing Avobenzone, may also help reduce long-term sun damage such as premature aging of the skin and skin cancer.


Q. Is avobenzone safe in sunscreen?

Avobenzone degrades rapidly in the sun and provides only around 30 minutes of sun protection. After only an hour in the sun, it loses 36% of its ability to absorb ultraviolet light.

Q. Does avobenzone cause cancer?

There is no evidence available regarding the carcinogenic nature of Avobenzone.

Q. Is avobenzone safe during pregnancy?

It is recommended to avoid the use of products containing avobenzone during pregnancy due to the possible risk of harm to the developing foetus.

Q. Is avobenzone the same as oxybenzone?

  • Avobenzone and Oxybenzone are two different products having different chemical structures and are used as UV filters in sunscreen products.
  • Oxybenzone is safe for use in sunscreens that are applied to human skin, however avobenzone is not since it can breakdown in the sun and generate damaging radicals.

Q. Is avobenzone the same as benzene?

Avobenzone is an oil-soluble ingredient derived from dibenzoylmethane that is used to absorb ultraviolet radiation in sunscreen products, whereas Benzene is an aromatic hydrocarbon with the formula C6H6 and the structure of alternating single and double bonds. Both are different organic compounds with different physical & chemical properties as well as applications.

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