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Amylmetacresol (1300-94-3)

Amylmetacresol Chemical Structure

What is Amylmetacresol?

Amylmetacresol (AMC) is derived from m-cresol and has a pentyl group linked to the sixth carbon atom in its structure. The pure substance melts at 24 °C (75 °F) and is soluble in water, ethanol, acetone, diethylether and oil. It is used in lozenges, employed for the symptomatic relief of throat and mouth infections.

The product is currently under development.
Name of Product Amylmetacresol
IUPAC Name 5-methyl-2-pentylphenol
Synonyms 6-Pentyl-m-cresol; 6-Amyl-m-cresol; Amylmetacresolum; amilmetacresol; 2-Amyl-5-methylphenol; Amylmétacrésol
CAS No 1300-94-3
Molecular Formula C12H18O
Molecular Weight 178.27 g/mol
Pubchem CID 14759
Pubchem SID 481739570

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Form) Clear or almost clear liquid, or Solid crystalline mass
2 Appearance (Colour) Colourless or Slightly Yellow
3 Melting Point 24 °C
4 Solubility Very soluble in acetone and in ethanol (96%)
Practically insoluble in water

Mechanism of Action

It is active against both bacteria and viruses owing to its antibacterial and antiviral properties. It functions by killing the bacteria that causes the infection or grows in when there is an infection in the mouth or throat.

In addition to this, it has also been shown to block sodium channels in a manner that is analogous to that of local anesthetics.


Side effects

The side effects which may occur upon the use of Amylmetacresol are-

  • Soreness of the tongue
  • Difficulty in breathing
  • Hypersensitivity reactions occurs rarely, showing symptoms such as swelling of the face, nausea or dyspepsia.


Q. Is Amylmetacresol safe in pregnancy?

There has not been sufficient research done on the Amylmetacresol’s efficacy or safety during pregnancy. It is thus preferable to avoid its use during pregnancy to minimize any potential risk.

Q. Is Amylmetacresol an antibiotic?

Amylmetacresol is an antibiotic.

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