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Indocyanine Green (Iodine free)

Indocyanine Green (Sodium iodide free) Chemical Structure

What is Indocyanine Green (Iodine free) ?

It is a type of cyanine dye that is specifically utilized in the field of medical diagnostics, particularly in the area of ophthalmology. In contrast to Indocyanine Green (ICG), it does not contain iodine.

Macsen Laboratories is the leading manufacturer and supplier of Indocyanine Green (Iodine free) with GMP and ISO certification.
Name of Product Indocyanine green (Iodine free)
Synonyms Infracyanine Green
CAS No 3599-32-4
Molecular Formula C43H47N2NaO6S2
Molar Mass 774.96 g/mol


SR. No Criteria Limit/Specification
1 Appearance Dark Olive Green or Dark Brown-Red powder
2 Solubility Freely soluble in water
3 Loss On Drying (50°C for 3 hr) NMT 6.0%
4 Related Substance
I. Specified Impurity
a. Acetanilide 0.06 %
b. ICG/KSM-II 0.14 %
c. Impurity (m/z= 348.3) 0.69 %
d. Cyclize Impurity 0.20 %
II. Total Impurity NMT 2.0 %


This Iodine free derivative of Indocyanine Green is used in patients allergic to iodine. It is primarily used in ophthalmology, particularly for enhancing visualization during eye surgery. Its uses include –

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