Tiaprofenic Acid (33005-95-7)

Chemical Structure of Tiaprofenic Acid

What is Tiaprofenic acid?

Tiaprofenic acid is a nonsteroidal anti-inflammatory medication used to treat pain, specifically arthritis pain. It belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDs) known as arylpropionic acid (profen). Structurally, it is a member of thiophenes, a monocarboxylic acid and an aromatic ketone.

The product is currently under development.
Name of Product Tiaprofenic acid
IUPAC Name 2-(5-benzoylthiophen-2-yl)propanoic acid
Synonyms Surgam; Tiaprofensaeure; 2-(5-benzoylthiophen-2-yl)propanoic acid; Acido tiaprofenico; Acide tiaprofenique; Acidum tiaprofenicum; 5-Benzoyl-alpha-methyl-2-thiopheneacetic acid; 2-(5-Benzyl-2-thienyl)propionsaeure; Tiaprofenate; Suralgan
CAS No 33005-95-7
Molecular Formula C14H12O3S
Molecular Weight 260.31 g/mol
Pubchem CID 5468

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Form) Solid Powder
2 Appearance (Color) White to Off-White
3 Melting Point 96 °C
4 Solubility Slightly soluble in DMSO and Methanol


Tiaprofenic acid is utilized predominantly for its anti-inflammatory, analgesic, and antipyretic properties. It is used to treat a variety of conditions characterized by inflammation, discomfort, and fever.

It is frequently prescribed for the management of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis symptoms. These conditions involve inflammation of the joints, which causes pain, edema, and decreased mobility. This medication reduces these symptoms. The standard dose for adults is 300 mg twice daily.

Side effects

Some of the side effects associated with the use of Tiaprofenic acid include-

  • Stomach pain or Ulcers
  • Nausea
  • Drowsiness/Dizziness
  • Headache
  • Constipation or Diarrhea


Q. What are the brand names of Tiaprofenic acid?

Tiaprofenic acid is generally available under the trade names like Surgam, Surgamyl, Artiflam, Flamirex, etc.

Q. Can Tiaprofenic acid be used for toothache?

Tiaprofenic acid can be used to relieve toothache pain. However, it should only be used upon consultation with a registered healthcare professional for proper dosage and to avoid any potential side effects or interactions.

Q. Is Tiaprofenic acid available over the counter?

Tiaprofenic acid is a prescription medicine and is not available over the counter.

Q. Is Tiaprofenic acid better than Ibuprofen?

Both Tiaprofenic acid and Ibuprofen are equally effective in giving pain relief and are a safe treatment option for patients suffering from pain associated with osteoarthritis.

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