Buparvaquone is a chemical compound belonging to the class of naphthoquinones. It is an antiprotozoal drug related to Atovaquone. It was first manufactured in Great Britain, followed by Germany.
|Name of Product||Buparvaquone|
|Synonyms||Butalex; Buparvaquonum; Buparvacuona; Buparvaquona; BW-720C|
|Molecular Weight||326.4 g/mol|
|1||Appearance (Form)||Solid Powder|
|2||Appearance (Colour)||Light Yellow|
|3||Melting Point||177-185 °C|
|4||Solubility||Ethanol: Slightly Soluble
DMF: 1 mg/ml
DMSO: 1 mg/ml
Buparvaquone binds to the Qo site of cytochrome b thus inhibiting Coenzyme Q – cytochrome c reductase and blocks the mitochondrial electron transport at complex III ( bc1 complex) of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death.
Q. What is the route of administration of Buparvaquone?
Buparvaquone is commonly administered intramuscularly via injection.
Q. Is Buparvaquone an antibiotic?
Buparvaquone is an antibiotic. It is an antiprotozoal agent.