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Ciclopirox Olamine (41621-49-2)

Ciclopirox Olamine Chemical Structure

What is Ciclopirox Olamine?

Ciclopirox Olamine is the olamine salt form of ciclopirox, a N-hydroxypyridone derivative. It is a synthetic antifungal agent with wide spectrum of activity, and it also possesses antibacterial and anti-inflammatory properties. It is used for the treatment of fungal infections of the skin and nails. It is especially helpful for treating tinea versicolor.

The product is currently under development.
Name of Product Ciclopirox Olamine
IUPAC Name 2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one
Synonyms Ciclopirox ethanolamine; ciclopiroxolamine; Batrafen; Micoxolamina; Brumixol; Mycoster; Ciclopiroxolamin; Ciclochem; Dafnegin
CAS No 41621-49-2
Molecular Formula C14H24N2O3
Molecular Weight 268.35 g/mol
Pubchem CID 38911
Pubchem SID 480474269

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Form) Solid Powder
2 Appearance (Color) White to Off-white to Slightly yellow
3 Solubility Soluble in DMSO and Methanol
4 Melting point 143.0 - 144.0 °C
5 pH 8.0-9.0
6 Residue on Ignition ≤0.1%
7 Loss on Drying ≤0.1%


Side effects

Side effects associated with the use of Ciclopirox Olamine include –

  • Redness, or itching at the application site
  • Mild burning or stinging sensation
  • Nails discoloration or other changes
  • Erythema


Q. Is Ciclopirox olamine cream a steroid?

Ciclopirox olamine belongs to the class of medications called antifungals.

Q. Can Ciclopirox olamine cream be used on the face?

According to some research, topical 1% Ciclopirox olamine cream is a safe and effective treatment for mild-to-moderate facial seborrheic dermatitis. However, one should use it with prior consultation from a medical professional and avoid contact with eyes, ears, nose and mouth.

Q. Is Ciclopirox olamine cream available over the counter?

Ciclopirox olamine cream is a prescription medication and is not available over the counter.

Q. How to use ciclopirox olamine cream?

The area to be treated must be thoroughly cleaned and dried. Apply a thin layer of the medication on and around the affected region and rub gently into the skin, typically twice daily or as instructed by your doctor.

Q. Can ciclopirox olamine be used for yeast infection?

It can be used for the treatment of yeast infections along with fungal infections.

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