What is Ciclopirox Olamine?
Ciclopirox Olamine is the olamine salt form of ciclopirox, a N-hydroxypyridone derivative. It is a synthetic antifungal agent with wide spectrum of activity, and it also possesses antibacterial and anti-inflammatory properties. It is used for the treatment of fungal infections of the skin and nails. It is especially helpful for treating tinea versicolor.
The product is currently under development.
| PRODUCT SPECIFICATIONS | |
|---|---|
| Name of Product | Ciclopirox Olamine |
| IUPAC Name | 2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one |
| Synonyms | Ciclopirox ethanolamine; ciclopiroxolamine; Batrafen; Micoxolamina; Brumixol; Mycoster; Ciclopiroxolamin; Ciclochem; Dafnegin |
| CAS No | 41621-49-2 |
| Molecular Formula | C14H24N2O3 |
| Molecular Weight | 268.35 g/mol |
| Pubchem CID | 38911 |
| Pubchem SID | 480474269 |
Chemical Properties
| SR. No | Criteria | Limit/Specification |
|---|---|---|
| 1 | Appearance (Form) | Solid Powder |
| 2 | Appearance (Color) | White to Off-white to Slightly yellow |
| 3 | Solubility | Soluble in DMSO and Methanol |
| 4 | Melting point | 143.0 - 144.0 °C |
| 5 | pH | 8.0-9.0 |
| 6 | Residue on Ignition | ≤0.1% |
| 7 | Loss on Drying | ≤0.1% |
Uses
- Ciclopirox Olamine is primarily used as a cream for the treatment of fungal skin infections such as Tinea pedis (Athlete’s foot), Tinea corporis, Jock itch (affects the groin area) and Ringworm infection.
- It is also used in the form of shampoo for the treatment of seborrheic dermatitis (a skin disorder characterized by scaly areas and red skin mainly on the scalp).
- Fungal infections of the fingernails and toenails can be treated with Ciclopirox nail lacquer.
Side effects
Side effects associated with the use of Ciclopirox Olamine include –
- Redness, or itching at the application site
- Mild burning or stinging sensation
- Nails discoloration or other changes
- Erythema
FAQs
Q. Is Ciclopirox olamine cream a steroid?
Ciclopirox olamine belongs to the class of medications called antifungals.
Q. Can Ciclopirox olamine cream be used on the face?
According to some research, topical 1% Ciclopirox olamine cream is a safe and effective treatment for mild-to-moderate facial seborrheic dermatitis. However, one should use it with prior consultation from a medical professional and avoid contact with eyes, ears, nose and mouth.
Q. Is Ciclopirox olamine cream available over the counter?
Ciclopirox olamine cream is a prescription medication and is not available over the counter.
Q. How to use ciclopirox olamine cream?
The area to be treated must be thoroughly cleaned and dried. Apply a thin layer of the medication on and around the affected region and rub gently into the skin, typically twice daily or as instructed by your doctor.
Q. Can ciclopirox olamine be used for yeast infection?
It can be used for the treatment of yeast infections along with fungal infections.
Resources on Ciclopirox Olamine
Ciclopirox Olamine | Properties, Mechanism of action & Uses
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