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Fenpiverinium bromide (125-60-0)

Fenpiverinium bromide Chemical Structure

What is Fenpiverinium bromide?

Fenpiverinium is a quaternary ammonium compound with anticholinergic and antispasmodic properties. It is used to treat pain and smooth muscle spasms and is marketed as a combination medicine in Eastern Europe and India. The combination treatment also contains pitofenone hydrochloride and either nimesulide or metamizole.

The product is currently under development.
Name of Product Fenpiverinium bromide
IUPAC Name 4-(1-methylpiperidin-1-ium-1-yl)-2,2-diphenylbutanamide;bromide
Synonyms 1-(4-amino-4-oxo-3,3-diphenylbutyl)-1-methylpiperidin-1-ium bromide; Fenpiverinium bromide [INN]; Resantin; Brometo de fenpiverínio; bromuro de fenpiverinio; Bromure de fenpiverinium
CAS No 125-60-0
Molecular Formula C22H29BrN2O
Molecular Weight 417.4 g/mol
Pubchem CID 71489
Pubchem SID 475523897

Chemical Properties

SR. No Criteria Limit/Specification
1 Appearance (Form) Solid
2 Appearance (Colour) White to Off-White
3 Solubility Methanol (Slightly), Water (Slightly, Heated)
4 Melting Point 213-217˚C
5 Storage Temperature 2-8˚C


Fenpiverinium Bromide is used to treat muscle pain and muscle spasms in smooth muscle. The following are some of the ways in which it contributes to the improvement of the patient’s condition:

  • Preventing the formation of the prostaglandins that are responsible for the pain.
  • Reducing the discomfort caused by spasms in smooth muscles.


Q. What is the combination of Pitofenone hydrochloride and Fenpiverinium bromide used for?

The combination of the anticholinergic drugs, Fenpiverinium bromide and Pitofenone hydrochloride, is used for the treatment of various stressful conditions associated with the pain and muscular contractions in the digestive tract, urinary tract and other organs.

Q. What is the mechanism of action of Fenpiverinium bromide?

Fenpiverinium Bromide, being an anticholinergic drug, works by blocking the neurotransmitter acetylcholine, eventually inhibiting the nerve impulses which are responsible for causing pain and muscular contractions, and is thus used as an antispasmodic agent.

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