SR. No | Criteria | Limit/Specification |
---|---|---|
1 | Appearance | greenish-blue colour |
2 | Heat Resistance °C | 160°C |
3 | Density, g/cm3 | 1.15 |
4 | Residue on 80mesh | 5.0 %max |
5 | Water Soluble | 1.0 % max |
6 | Volatile Matter at 105°C | 1.0 %max |
7 | Tinting Strength | 95-105 % |
Isosulfan Blue is a visual lymphatic imaging agent that is synthesised. It is injected into the tumour site’s periphery, where it binds to the lymphatic system and assists in the surgical detection of tumour sentinel nodes that stain blue.
It is also utilised as a contrast agent to identify lymphatic vessels in teenage varicoceles with high retroperitoneal ligation and to detect lymphatic vessel leakage after surgery. It is used in conjunction with lymphography to see the lymphatic system draining the injection site (in primary and secondary lymphedema of the limbs; chyluria, chylous ascites or chylothorax; lymph node involvement by the main or secondary tumour).
Although it is a fairly safe dye, several incidences of anaphylactic shock have been observed after receiving this medication.