The salt generated by lanthanum(III) cations and carbonate anions is lanthanum carbonate, La2(CO3)3. It is used as a Phosphate binder medication for controlling hyperphosphatemia in patients with chronic renal failure who are on renal dialysis.
It is taken with meals to bind with dietary phosphate, preventing phosphate absorption in the gut. However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral oedema, should be clinically monitored. Bayer Animal Health sells it under the brand name Renalzin for cats suffering from hyperphosphatemia. It is also used in the production of certain high-temperature superconductors.
The product is currently under development. Samples are available from R&D. US DMF will be filed this year.
| PRODUCT SPECIFICATIONS | |
|---|---|
| Name of Product | Lanthanum Carbonate |
| Pharmacopoeial Name | Lanthanum Carbonate. |
| Synonyms | Fosrenol; Lanthanum sesquicarbonate; lanthanum(3+) salt (3:2); lanthanum(3+) tricarbonate |
| CAS No | 587-26-8 |
| Molecular Formula | La2(CO3)3 |
| Molecular Weight | 457.84 gm/mol |
| Density | 2.6–2.7 g/cm3 |
| Pubchem CID | 168924 |
| Pubchem SID | 462770289 |
TECHNICAL SPECIFICATIONS
| SR. No | Criteria | Limit/Specification |
|---|---|---|
| 1 | Appearance (Color) | White |
| 2 | Appearance (Form) | powder |
| 6 | Nature | Hygroscopic |
| 3 | Solubility | Soluble in acids & Insoluble in water |
| 4 | Density | 2.6 g/cm3 |
| 5 | Purity | 99% |
| 6 | Shelf Life | 60 months |
