Lanthanum Carbonate (587-26-8)

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The salt generated by lanthanum(III) cations and carbonate anions is lanthanum carbonate, La2(CO3)3. It is used as a Phosphate binder medication for controlling hyperphosphatemia in patients with chronic renal failure who are on renal dialysis.

It is taken with meals to bind with dietary phosphate, preventing phosphate absorption in the gut. However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral oedema, should be clinically monitored. Bayer Animal Health sells it under the brand name Renalzin for cats suffering from hyperphosphatemia. It is also used in the production of certain high-temperature superconductors.

The product is currently under development. Samples are available from R&D. US DMF will be filed this year.
PRODUCT SPECIFICATIONS
Name of Product Lanthanum Carbonate
Pharmacopoeial Name Lanthanum Carbonate.
Synonyms Fosrenol; Lanthanum sesquicarbonate; lanthanum(3+) salt (3:2); lanthanum(3+) tricarbonate
CAS No 587-26-8
Molecular Formula La2(CO3)3
Molecular Weight 457.84 gm/mol
Density 2.6–2.7 g/cm3
Pubchem CID 168924
Pubchem SID 462770289

TECHNICAL SPECIFICATIONS

SR. No Criteria Limit/Specification
1 Appearance (Color) White
2 Appearance (Form) powder
6 Nature Hygroscopic
3 Solubility Soluble in acids & Insoluble in water
4 Density 2.6 g/cm3
5 Purity 99%
6 Shelf Life 60 months

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