Its primary application is in the treatment of schizophrenia and other psychotic disorders as part of ongoing maintenance or long-term therapy.
|Name of Product||Penfluridol|
|Synonyms||Micefal; Penfluridol; Penfluridolum; Semap; Longoperidol|
|Molecular Weight||524.0 g/mol|
|2||Appearance (Colour)||White to Beige|
|3||Melting Point||106.0 to 110.0 °C|
|4||Solubility|| DMSO: >20 mg/mL
Penfluridol falls under the category of an antipsychotic drug. It works by inhibiting the function of the chemical messenger dopamine, which is responsible for influencing both thoughts and feelings, within the body. This is facilitated by the drug’s ability to bind with dopamine receptors, so it blocks the mesocortical as well as the mesolimbic dopaminergic pathways.
It is also being used in some research studies as mentioned below:
The side effects associated with the use of Penfluridol are as follows:
Blood disorders, severe heart disease, and orthostatic hypotension (sudden lowering of blood pressure on standing) are some of the significant adverse effects that can occur
Q. Who should not take Penfluridol?
It is contraindicated in people with preexisting depression or coma of the central nervous system.
Q. What is the dosage of Penfluridol?
Due to its exceptionally long-lasting effects, it is frequently suggested to be taken orally only once each week (q 7 days). The once-weekly dose ranges from 10 to 60 mg.
Q. How should Penfluridol be taken?
It is a tablet to be taken orally, with or without food.