Quinfamide (Quinfamida) (62265-68-3)

Quinfamide Chemical Structure

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What is Quinfamide (Quinfamida)?

Quinfamide or Quinfamida is a member of the class of organic compounds known as quinolines. Pharmacologically, It belongs to a small class of antiamoebic chemicals having a dichloroacetamide functional group and has anti-parasitic properties.

Quinfamida is usually used in combination with Albendazole or  Mebendazole for the treatment of a number of parasitic worm infestations including ascariasis, pinworm infection, hookworm infections, guinea worm infections, hydatid disease, giardia and also in Neurocysticercosis.

The product is currently under development. Samples are available from R&D.
PRODUCT SPECIFICATIONS
Name of Product Quinfamide
IUPAC Name [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl] furan-2-carboxylate
Synonyms Quinfamide; Amenide; Amenox; 1-(Dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline; Quinfamida; Quinfamido
CAS No 62265-68-3
Molecular Formula C16H13Cl2NO4
Molecular Weight 354.2 g/mol
Pubchem CID 71743
Pubchem SID 463949366

Uses

  • Quinfamide is a dichloroacetyl quinolol that is used to treat chronic and subacute intestinal amoebiasis. Several dose-ranging studies have found quinfamide to be beneficial at total doses of 300, 600, or 1,200 mg.
  • Quinfamide has also been used in clinical trials studying the treatment of Amoebiasis and Helminthiasis.

Side effects

The most common side effects associated with the use of Quinfamide include headache, nausea, and abdominal pain. The majority of the time, these effects are modest and transitory.

FAQs

Q. What is Amefin Quinfamide 300 mg used for?

It is indicated in the treatment of acute intestinal amoebiasis or in chronic intestinal amoebiasis.

Q. Who manufactures Quinfamide?

Macsen Lab is the leading manufacturer and supplier of Quinfamide with ISO certification.

Q. What is Quinfamida used for?

Quinfamida is indicated for the treatment and prophylaxis of intestinal amoebiasis in its two forms: active acute amoebiasis and asymptomatic carrier status. It should be noted that amoebicide treatment with quinfamide is rendered in 24 hours.

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