2,4-Dichlorobenzyl Alcohol EP (1777-82-8)

What is 2,4-Dichlorobenzyl Alcohol?

2,4-Dichlorobenzyl alcohol (DCBA) is an aromatic chlorinated alcohol widely used as a mild antiseptic and antimicrobial agent. It helps to prevent mouth and throat infections by inhibiting the growth of bacteria and fungi in the oral and upper respiratory tract.

2,4-Dichlorobenzyl alcohol is combined with amylmetacresol to exhibit the synergistic effects and helps to enhance its efficacy against a broad spectrum of microorganisms.

Mechanism of Action 

• 2,4-Dichlorobenzyl alcohol exhibits its antibacterial properties by helping in denaturation of bacterial proteins and dissolution of lipids, which leads to disruption of the cell membrane and subsequent cell lysis.
• It also lowers sodium channel activity to provide local anesthetic effects and helps to relieve the throat from pain and irritation.

Uses

• 2,4-Dichlorobenzyl alcohol is added to oral dosage medications such as lozenges and troches for the symptomatic relief of sore throat and mild mouth and throat infections.
• It is used to help manage throat infections, including pharyngitis (inflammation of the pharynx) and minor oral infections.
• It may also help reduce microbial load and provide soothing relief from irritation associated with cough, mouth ulcers, and throat discomfort.

Side Effects 

Common side effects related to 2,4-Dichlorobenzyl alcohol are as follows-

• Hypersensitivity
• Allergic Reaction
• Mild burning sensation
• Numbness in the oral cavity
• Localized redness at the site of application
• Stinging sensation
• Tongue discomfort or soreness

FAQs

Q. What is 2,4-Dichlorobenzyl alcohol used for?

2,4-Dichlorobenzyl alcohol is an organic compound member of the benzyl alcohol class. It is added in oral antiseptics and throat lozenges to cure acute sore throat caused by upper respiratory tract infections.

Q. Is Dichlorobenzyl alcohol good for a cough?

2,4-Dichlorobenzyl alcohol is effective against cough, as it helps to soothe irritation in the throat.

Q. What are the side effects of Dichlorobenzyl alcohol?

2,4-Dichlorobenzyl alcohol is generally safe, however, it may cause a mild burning sensation and numbness in the mouth.

Q. Is Dichlorobenzyl Alcohol safe during pregnancy?

Dichlorobenzyl alcohol is generally safe, and it is available as over-the-counter lozenges and considered low risk during pregnancy when used in small, topical amounts, such as in throat lozenges.