Acriflavine BPC 63 (HCl) (8063-24-9)

ACRIFLAVINE BPC 63

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What is Acriflavine

Acriflavine is a fluorescent dye that can be applied to the skin as a topical antiseptic and is also used in biological staining. It occurs as a brownish-orange powder. Acriflavine was discovered in 1912 as a byproduct of coal tar by Paul Ehrlich, and its first application was during WWI for treating parasites that caused sleeping sickness. It is known to be effective for parasitic infection treatment. It is also used to treat external fungal infections in aquarium fish, as well as minor wounds, burns, and infected skin.

Macsen Laboratories is a GMP & ISO certified manufacturer & supplier of high-quality Acriflavine BPC.
PRODUCT SPECIFICATIONS
Name of Product Acriflavine HCl
Pharmacopoeial Name Acriflavine BPC 63
Synonyms Acriflavin Hydrochloride; Acriflavine; Mixture of 3,6-Diamino-10-methylacridinium chloride and 3,6-acridinediamine; Chromoflavine; Neutroflavine; Xanthacridine; Acriflavon; Trypaflavine; Gonacrine; Gonacrin; Panflavin; Acriflavina
CAS No 8063-24-9
Molecular Formula C27H28Cl4N6
Molecular Weight 578.4 g/mol
Pubchem CID 53393742
Pubchem SID 462730480
GMP
DMF

Chemical Properties

SR. No Criteria Limit/Specification Our Results
1 Description Orange- Red to Red Crystalline Powder, Odourless,
Taste Acid
Orange- Red to Red Crystalline Powder, Odourless.
2 Solubility Must Pass B.P.C-63 Test Passes B.P.C-63 Test
3 Identification Must Pass 1 to 5 B.P.C-63 Tests Passes 1 to 5 B.P.C-63 Tests
4 Water Insoluble Matter Test Must Pass B.P.C-63 Test Passes B.P.C-63 Test
5 Certain Other Acridine Derivative Test Must Pass B.P.C-63 Test Passes B.P.C-63 Test
6 Water NMT6.5% 3-4%
7 Sulphated Ash Test NMT 1.0% 0.5-0.8 %
8 Assay (With Reference To Anhydrous Subs. & As % Of C14h14n3cl) MINIMUM 98.5% TO 105.0% MAXIMUM 99.5-103.5%

Uses

Uses of Acriflavine

  • Acriflavine is a fluorescent labelling agent for high molecular weight RNA in biochemistry.
  • It is also being researched since 2014 as an antimalarial drug.
  • It was also used to treat gonorrhoea but was later replaced by antibiotics.
  • It is still used as a topical antiseptic for treating contaminated or suppurating (weeping) wounds.
  • Acriflavine in aquaculture is used in the treatment and prevention of the diseases of fish such as Columnaris Infections, Velvet and Ich infections, Saprolegnia spp. Infections, Fin and egg rot infections, for the disinfection of fish eggs, treatment of open wounds, and treatment of external protozoan infections.

Side effects

Commonly associated negative effects with Acriflavine-containing drugs are as below:

  • Vomiting
  • Dizziness
  • Nausea
  • Headache
  • When used for fish, Acriflavine is believed to cause infertility and can be stressful for many fishes at a high dosage.

This isn’t a complete list. Although some of the side effects are rare, others are dangerous. Contact your doctor if you have any of the side symptoms, especially if they persist.

Precautions

Before using Acriflavine, tell your doctor about all of your current prescriptions, over-the-counter goods (such as vitamins and herbal supplements), allergies, pre-existing disorders, and current health issues (e.g., pregnancy, upcoming surgery, etc.). If you have certain medical problems, you may be more sensitive to the drug’s negative effects. Follow your doctor’s instructions or the product insert’s instructions. The dosage is fixed by your medical condition. Contact your doctor if any of your issues persists or worsens.

FAQs

Q. Is Acriflavine habit-forming or addictive?

Most medicines are free of the risk of addiction or abuse. Medications that can be addictive are usually classified as controlled substances by the government. In India, schedule H or X is an example, while in the United States, schedule II-V is an example. Acri is not reported as a controlled substance in almost all countries except Australia where it is considered either a Schedule 5 (Caution) or Schedule 7 (Dangerous Poison) substance.

Q. Is acriflavine safe for fish?

Acriflavine can be used as a short term bucket dip for fish, or it can be added to the aquarium water to treat the entire tank, preventing higher dosage as it may be stressful for many fish. Also, it severely damages live plants and stains artificial plants and other decorations in the tank.

Q. How to use acriflavine for fish?

Acriflavine can be used as a short term (5 minutes to 1 hour) or long term bath (3 days to 3 weeks) for fish or it can be added to the aquarium water to treat the entire tank. Topical application is sometimes used on wounds to help prevent bacterial infection.

Q. Where to buy Acriflavine?

Macsen Laboratories is a GMP and ISO-certified manufacturer and supplier of various grades of high-quality Acriflavine.

Buy the best quality Acriflavine BPC 63 for Veterinary, Aquaculture & Human Use from Macsen Laboratories.

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